The panel discussion on Operational Excellence with IIoT and Advanced Analytics highlighted the importance of machine data in driving operational excellence, as well as the need for effective strategies to integrate and analyze time series data in real-time. The panelists emphasized the benefits of using IoT and advanced analytics to optimize manufacturing processes, improve worker skills, and enhance safety measures. They also discussed the challenges of collecting and analyzing machine data, and how to overcome them. Key takeaways included the importance of having an open ecosystem, strong data governance policies, and robust cybersecurity measures in establishing a successful IoT infrastructure. Additionally, emerging trends like generative AI, edge analytics, and sustainability are shaping the future of industrial analytics, with the operationalization of AI being a major trend that is expected to lead to smarter, more efficient, and more adaptable production processes.