The Firebase Genkit framework is a powerful tool for building generative AI applications, providing essential tools such as models, prompts, indexers, retrievers, flows, traces, and evaluations. To build a Retrieval-Augmented Generation (RAG) application with Genkit and Astra DB, developers need to create a database and collection within Astra DB, install Genkit and related dependencies into their Node.js application, configure Genkit with their Astra DB credentials, and then start creating flows. These flows can be used to ingest data from a URL, retrieve context from the database, generate responses based on the context, and perform vector search using the Astra DB retriever. The process of building an RAG application takes fewer than 100 lines of code, making it relatively straightforward, thanks to Firebase Genkit's ease of use and powerful features such as tracing that helps track down bugs in flows.