DreamFactory is a key topic of discussion in the latest episode of The NoSQL Database Podcast, where Jason Gilmore shares his expertise on using DreamFactory to generate and manage APIs over various platforms, including databases. Jason introduces listeners to DreamFactory, highlighting its ability to handle NoSQL data, and discusses several use cases, such as customer 360 integration and business logic implementation. The conversation also touches on additional non-database integrations, performance optimization, indexing, logging/monitoring, and profiling, providing a comprehensive overview of DreamFactory's capabilities.