This tutorial discusses how to deploy YugabyteDB with Istio mTLS to secure communication between services in a microservices architecture. It sets up a YugabyteDB cluster via Helm and enables peer authentication policies, destination rules, and mutual TLS connections for services within the same namespace. The tutorial also uses Kiali to visualize mesh traffic and demonstrates how to offload security concerns to Istio. By using Istio with YugabyteDB, developers can focus on building modern apps backed by a distributed database while leveraging the benefits of a zero-trust network security approach.