You can get up and running with PGAdmin on a distributed SQL database like YugabyteDB by installing the latest version of PGAdmin, setting a master password, adding a new server connection object, and exploring the Northwind sample database using the tool's intuitive user interface. With features such as a simple to use connection wizard, built-in SQL editor, and auto-generation of SQL scripts, PGAdmin simplifies database management and increases productivity for developers. After installing PGAdmin on a Mac or other supported operating environments, users can view database objects, query data, and explore the Northwind sample database to get started with YugabyteDB.