This walkthrough guides developers on connecting a Spring Boot application to YugabyteDB Managed, a cloud-native SQL database service. The process involves creating a free account and cluster, cloning the Spring Boot PetClinic sample application, containerizing it, starting minikube, and deploying the image to create a Kubernetes cluster with a load balancer. The application is then made available at a specified URL, allowing developers to test its functionality on the YugabyteDB database cluster.