The project Sushi is an AI-powered virtual assistant that utilizes OpenAI's GPT-3.5 Turbo model for conversation generation and Vonage Video Live Captions for speech-to-text functionality. The setup involves a Node.js application that streams data from the GPT API, converts it into audible speech using the browser's native SpeechSynthesisUtterance module, and manages interruptions from users speaking. The assistant is designed to mimic real-life interactions, allowing users to interrupt and guide the conversation. The project showcases the potential of integrating AI models with video conferencing platforms, enabling more engaging and productive virtual meetings.