WireGuard is a modern VPN protocol that aims to deliver performance, strong encryption capabilities, and a secure code base. Its kernel-level support for Windows has raised questions about its readiness to replace IPsec and OpenVPN. While WireGuard can outperform other protocols in terms of performance, it also has tradeoffs, such as limited federal approval and potential privacy concerns. Businesses may consider using WireGuard when they need a lightweight and secure solution, but larger organizations with specific use cases should carefully evaluate the risks and capabilities relative to IPsec or OpenVPN. Additionally, Twingate offers a more secure and performant alternative to WireGuard VPN based on a Zero Trust framework.