Twilio Verify Service can be integrated with RSA SecurID to provide an alternative multi-factor authentication solution for organizations using hardware tokens. This integration allows employees to log in protected systems by receiving a One-Time Password (OTP) delivered to their mobile phone, reducing support costs and improving user experience. To achieve this, Twilio Functions are used as a proxy between RSA Authentication Manager and the Twilio Verify service, requiring a custom code feature to be enabled. The process involves setting up a Twilio Verify Service, creating a Twilio Function, configuring RSA Authentication Manager, and updating certificates to ensure secure communication between the services.