Twilio is used to send an MMS (Multimedia Messaging Service) with a gopher gif, created using Go programming language. To start, one needs to have a Twilio account and phone number, as well as the Go programming language installed. The twilio-go package is then installed, followed by creating a new Go program that imports the necessary libraries. A client variable is initialized with Twilio credentials, and a gif is parsed using the `url.Parse` method from the net/url library. Then, an MMS message is sent to a specified recipient number using the `client.Messages.SendMessage` method, which requires the sender's Twilio number, recipient number, and the gif as the message body. Finally, the program prints out the status of the sent message. The example code demonstrates how easy it is to send a gopher gif with Twilio using Go, and encourages further exploration of possibilities such as integrating this idea into an existing app or building an app using concurrency with Go's goroutines.