To build more durable, profitable customer relationships in a challenging macro environment, companies must get smarter about customer acquisition. They need to leverage data-driven strategies that focus on higher-quality relationships rather than throwing more money at the problem. Five key lessons from Twilio's SIGNAL 2022 vision keynote highlight effective digital customer engagement tactics, including real-time customer knowledge, conversational messaging, frictionless onboarding, leveraging data to build customer loyalty, and empowering agents as trusted advisors. By implementing these strategies, companies can lower their cost per acquisition (CAC) and increase lifetime value (LTV), ultimately driving business growth in 2023.