The key to success in Startup Weekend Mobile SF is maximizing productivity while managing expectations and building a culture that launches. To achieve this, individuals should bring their own internet connection, use free tools like WordPress and Google Apps, recruit developers first, focus on getting proof of concept fast with minimal features, pick an idea they know how to build, get customers right away, and start planning presentations early. By following these principles, teams can create a productive environment, manage expectations, and ultimately launch a successful product.