You can generate images using DALL·E 2 and Twilio SMS with Python. To start, you need a free Twilio account, a phone number with SMS/MMS capabilities, Python 3.9, a code editor or IDE, a free OpenAI account, ngrok, and an OpenAI API Key. You can create an image by sending a text message to your Twilio number, which will trigger the generation of an image based on the prompt from the incoming message. The generated image is then sent back as an MMS response.