Twilio Programmable Voice allows employees to work from home by creating a solution that enables remote working with Twilio, SIP softphone software or an SIP IP Phone. To start, create a TwiML bin to allow the remote worker to place outbound calls and associate it with a purchased Twilio number. Next, configure a SIP domain for your account, which is similar to a phone number in the PSTN. This allows you to register your softphone to your Twilio account. Connect a softphone to your Twilio SIP endpoint using Zoiper's softphone or another softphone application like X-Lite. Alternatively, connect an IP Phone like OBi2162 from Obihai to your Twilio SIP endpoint. The setup involves navigating to the Configuration Dashboard and selecting "Service Provider Set-up" -> OBiTALK Compatible Service Providers -> Twilio, where you can enter your Domain, Username, and Password. Once set up, your softphone or IP Phone should be able to place calls from home and receive incoming calls.