A Raspberry Pi-based emergency call button system can be built using Twilio Programmable Voice, allowing users to quickly call for help with just a push of a button. The system uses Python programming language and the RPi.GPIO library to connect the button to a signal that triggers a phone call to a designated relative or recipient through Twilio's voice API. With the system assembled and programmed, users can customize it by setting up their own phone numbers, relative numbers, and help text messages, making it a valuable tool for those in need of quick assistance during emergencies.