The article discusses how to verify phone numbers without using regular expressions, leveraging the Twilio Lookup API. It begins by setting up a basic Node.js project with Express and serving an HTML form that prompts users to enter their phone number. The server-side code uses the Twilio helper library to make requests to the Lookup API, which returns a HTTP 404 response if the number is invalid, indicating that it's not a valid phone number. The article then shows how to consume this route from the front-end using JavaScript and the Fetch API, verifying the input number in real-time and displaying visual feedback to the user based on the validity of the number.