You can hang up all currently in progress, ringing or queued Twilio phone calls using Python with the following steps. First, install Virtualenvwrapper to manage virtual environments and then create a virtual environment for your project, installing Twilio inside it. You'll need to set your Account SID and Auth Token as environment variables before running the script. The script uses `TwilioRestClient` to iterate over calls in different statuses (queued, ringing, or in progress) and hang up each call using the `hangup()` method. To make this process more convenient, you can turn it into a shell command that runs the script with a virtual environment activated.