React and Angular are two leading JavaScript frameworks used for building modern web applications. React, developed by Facebook/Meta, is a UI library that offers flexibility, Virtual DOM performance, and a gentler learning curve, making it suitable for dynamic interfaces, startups, and teams prioritizing rapid development. On the other hand, Angular, created by Google, is a complete, opinionated framework with built-in tooling, TypeScript integration, and comprehensive structure, ideal for enterprise applications and teams that value consistency and maintainability. Both frameworks integrate seamlessly with headless CMS solutions like Strapi v5, providing flexible content modeling, simple API integration, separated concerns, and performance benefits. When choosing between React and Angular, consider project scale and complexity, team skills and familiarity with TypeScript, development speed versus long-term maintainability, and future scalability and ongoing maintenance needs. Ultimately, select the framework that best matches your team's workflow, helping you build maintainable, scalable, and successful applications tailored to your business objectives.