SQL injection attacks are a significant threat to Node.js applications, occurring when user input is mishandled and used within SQL queries without proper validation, sanitization, or query construction. This can lead to unauthorized access, data leakage, and other security issues. To prevent SQL injection vulnerabilities in Node.js, developers can use query placeholders, prepared statements, validate and sanitize user input, and utilize the latest versions of ORM and SQL libraries. Additionally, using a Snyk IDE extension for Visual Studio Code can aid in identifying and resolving SQL injection vulnerabilities, providing real-time feedback during the coding process. By implementing these strategies, developers can ensure their Node.js applications are robust and secure against SQL injection attacks.