I've mastered Docker Compose by following four best practices: organizing my Compose file to prioritize developer happiness, using the default docker-compose.yml file for simple "start the whole solution" commands, utilizing docker-compose.override.yml for custom settings, and leveraging the YAML "entrypoint:" object to run a custom entrypoint script just for development needs. By adopting these strategies, I've significantly improved my development workflows and streamlined my team's environment setup with Docker Compose.