Selendroid and Appium are two popular mobile test automation tools that support Android app testing. Selendroid is a good option for developing only Android apps, offering backward compatibility from API 10 to API 19, and features like hot plugging and integration with Selenium Grid. However, its limitations make it less versatile than Appium. Appium, on the other hand, supports both Android and iOS app testing, has an easier experience without requiring SDKs or recompiling applications, and offers a UI inspector. Although Selendroid is bundled into Appium, Appium's larger user community and faster development pace give it an edge. As of now, Appium is the stronger choice for most software teams due to its versatility and enterprise-ready features.