The challenges of mobile testing include deciding which test automation framework to use, staying agile with testing, integrating testing with DevOps tools, and incorporating ITIL processes. To overcome these hurdles, it's essential to choose the right framework that addresses specific needs, adopt an Agile approach to ensure structure and consistency, integrate testing with CI/CD pipelines, and leverage ITIL principles for reproducibility and consistency. By addressing these challenges, organizations can establish a world-class mobile development life cycle.