Replit and Rails are philosophically aligned as they both aim to simplify development by removing unnecessary configuration and complexity. However, Replit's initial inability to work well with Rails was a limitation due to its focus on small and lightweight projects. Recently, Replit's infrastructure has improved, allowing it to support Rails applications, resulting in a delightful experience for users. With the help of the getting started guide and minimal modifications, developers can quickly set up a Rails project on Replit, taking advantage of its powerful infrastructure to build and deploy their applications.