The benefits of application caching are speed and efficiency in accessing data, but maintaining cache consistency is a significant challenge due to three main pitfalls: when changes to the primary database aren't reflected in the cache, there's a delay in updating cached results, and inconsistency across cached nodes. Cache inconsistency can have severe consequences, such as damaging customer trust and reputation, and even legal jeopardy. Fortunately, solutions like cache invalidation, write-through caching, write-behind caching, and Redis Enterprise's active-active geo-duplication can address these challenges and ensure reliable delivery of consistency in enterprise-level database caching.