Pulumi has introduced a new MySQL provider that allows users to manage MySQL databases and instances across various clouds, including AWS, Azure, and GCP, enhancing the end-to-end provisioning of database infrastructure. The article provides a tutorial on using this provider to handle permissions, create databases, and perform other common tasks, demonstrating scenarios involving both existing MySQL servers and new AWS RDS instances. It outlines how to set up configurations, deploy infrastructure, and manage users and permissions, emphasizing that passwords are securely handled as Pulumi Secrets. The guide concludes by encouraging users to explore more capabilities of Pulumi via GitHub or the Pulumi Community Slack channel.