Werner Vogels, AWS CTO, delivered a keynote at re:Invent 2018, sharing his experiences and insights on building reliable, scaleable, and secure cloud systems. He discussed various topics including databases, serverless computing, development tools, and architecture best practices. Werner highlighted the importance of reliability, scalability, and performance in minimizing the impact of failures and emphasized that cloud-native databases are the foundation of innovation. He also introduced new features such as AWS Lambda Layers and the Firecracker virtualization platform, which offer better isolation and efficiency for serverless environments. Additionally, Werner announced several toolkits and services to support modern development, including IDEs, languages, and workflows. The keynote concluded with the introduction of Now Go Build, a video series featuring startups that use cutting-edge software powered by AWS.