In today's complex technological landscape, maintaining robust and reliable infrastructure is crucial for businesses to deliver seamless digital experiences to their customers. Root cause analysis (RCA) is a systematic approach to problem-solving that aims to identify and address the underlying causes of incidents or anomalies within an infrastructure. Infrastructure monitoring plays a pivotal role in supporting effective RCA by providing real-time visibility into the performance and health of infrastructure components. This includes collecting and visualizing data, generating alerts and anomaly detection, log management and correlation, integration with other monitoring tools, historical data analysis, and leveraging the right tools for RCA. To conduct an effective RCA, organizations should establish a standardized process, use appropriate tools, involve multiple stakeholders, document results, and continuously improve the process. By following these best practices and using infrastructure monitoring platforms like New Relic, businesses can maximize their infrastructure monitoring capabilities to support effective root cause analysis and prevent incidents from recurring.