Chain-of-Thought (CoT) reasoning emphasizes step-by-step thinking in a linear format, helping language models break down problems into human-readable steps. In contrast, Tree-of-Thought (ToT) reasoning explores multiple possible paths simultaneously, evaluates them, and adapts accordingly. CoT is suitable for tasks that require structured, linear workflows, speed, and interpretability, while ToT excels in complex, open-ended domains where exploration and adaptation are necessary. Hybrid systems combining both approaches can leverage the strengths of each framework to achieve more robust problem-solving.