MSTest is a popular open-source test framework integrated with Visual Studio IDE, preferred by many developers over other C# frameworks for test automation, due to its ease of setup and comprehensive features like parallel test execution and data-driven testing. The latest version, MSTest V2, offers cross-platform compatibility and extensibility, making it a strong choice for Selenium C# testing. The tutorial outlines a step-by-step process for setting up the MSTest framework, including downloading Visual Studio, signing in for enhanced features, and installing necessary packages via the NuGet Package Manager or package manager commands. With a focus on beginners and professionals, the guide aims to simplify the setup process and enhance testing capabilities using MSTest with Selenium C#, encouraging users to share their experiences and feedback.