The Chrome Debugger is a powerful tool for front-end developers to debug JavaScript source code, offering features such as console logs, breakpoints, variable inspection, network activity analysis, and memory optimization. To use the debugger, developers can enable it via keyboard shortcuts or by opening the browser menu, then navigate to the Sources panel to set breakpoints, view source code, and inspect variables. The debugger also includes a console panel for executing JavaScript statements and viewing log output. Additionally, the Chrome Debugger offers advanced features such as memory analysis and security auditing, making it an essential tool for debugging complex web applications.