The narrative describes the transformative impact of integrating large language models (LLMs) and AI into manufacturing processes, highlighting the paradigm shift from the fourth industrial revolution, centered on data architecture and automation, to the fifth, characterized by AI advancements. The author shares personal experiences of leveraging AI tools like GPT-3.5 and GPT-4 to enhance decision-making and operational efficiency in a pharmaceutical manufacturing context, showcasing how these technologies can offload routine tasks and optimize production schedules. Through practical examples, the text illustrates significant financial benefits, including substantial net present value (NPV) and internal rate of return (IRR) from AI adoption across multiple sites. The author emphasizes the urgency of embracing AI rapidly to maintain competitive advantage, as even leading manufacturers are only beginning to explore proof-of-concept implementations. The discussion foreshadows further insights on building AI-friendly architectures in the subsequent blog post.