The SQLite plugin for Cordova is a highly sought-after tool that allows developers to create a full SQLite database, bypassing browser-based storage, which can be daunting for those unfamiliar with database queries. To simplify its usage, the screencast suggests using PouchDB as an abstraction, making it easier to handle data storage by treating it like a regular JavaScript object that translates into a SQL data store. The provided code snippet demonstrates setting up PouchDB with a 'websql' adapter, handling database changes, storing data, and retrieving documents. The screencast aims to make integrating the SQLite plugin into applications more accessible, while also promoting additional resources and updates through a newsletter subscription.