Mobile app development teams are responsible for ensuring HIPAA compliance, as platforms like Ionic provide the necessary building blocks but do not manage user data or network security directly. Ionic's tools, such as Identity Vault and Encrypted Storage, facilitate secure data storage and encryption, using device capabilities like iOS Keychain and Android Keystore to protect sensitive information with biometric authentication and secure data at rest. Network transport security is crucial, requiring SSL for all data transmissions and techniques like SSL pinning to prevent attacks. Protecting screen data during app suspension and adhering to API terms of service are critical for maintaining compliance. While Ionic focuses on the frontend, collaboration with backend teams is essential for overall HIPAA compliance, with Ionic offering solutions to streamline the development of secure, compliant mobile health apps across multiple platforms.