NVIDIA's Nemotron-Personas-USA is a privacy-preserving, open dataset developed using synthetic data validated against U.S. Census distributions, designed to provide a transparent and safe foundation for AI systems. Built with NVIDIA NeMo Data Designer, the dataset features 6 million synthetic American personas covering all U.S. states and territories, reflecting realistic demographic, occupational, and behavioral traits to mirror the diversity of the U.S. population without exposing any personally identifiable information. The dataset, licensed under CC BY 4.0, is intended for AI developers, researchers, and policy teams focused on building Sovereign AI solutions that incorporate U.S. cultural and contextual elements. It supports various applications, from minimizing sensitive data risks in AI model development to enabling "what-if" simulations for policy forecasting, while maintaining compliance and offering high utility on downstream tasks. This release is part of NVIDIA's expanding Nemotron-Personas collection, which also spans Japan and India, supporting Sovereign AI development and localized model fine-tuning globally.