Django is a popular Python framework for building full-stack applications, and it supports multiple databases, including Fauna, a serverless database. Fauna offers ease of use, serverlessness, and document-relational capabilities, making it an attractive option for developers. To use Fauna with Django, developers can install the Fauna open-source Python driver, create a new collection in their Fauna database, and then integrate the Fauna driver into their Django models. This integration allows developers to easily manage data using Django models without applying migrations. The Fauna Python driver provides methods for creating, reading, updating, and deleting data, making it easy to interact with the Fauna database from within a Django application. Developers can find examples of using Fauna with Django in various projects and tutorials, including a complete example of a Django project with Fauna.