Navigating the complex responsibilities of a security leader involves balancing strategic and operational initiatives to protect organizations from dynamic cybersecurity threats. Key responsibilities include risk management, which focuses on identifying and addressing vulnerabilities before they escalate, and internal collaboration across departments to align cybersecurity initiatives with business goals. Strategic planning for emerging threats, continuous security assurance through audits and testing, and robust security governance are crucial for maintaining a resilient defense. Managing third-party vendors to minimize risks and prioritizing security training for employees to prevent human error are also essential. External collaboration with peers and industry research helps stay informed about the latest trends and threats, while incident monitoring ensures quick responses to breaches. Although it is challenging to excel in every responsibility due to time and resource constraints, identifying areas that require more attention and reallocating time accordingly is vital. The priorities of security leaders can vary based on organizational factors, and a survey of 130 CISOs and CSOs highlights these differing priorities.