A new report by Dynatrace reveals significant challenges faced by the retail industry in managing software vulnerabilities amid increasing reliance on dynamic multicloud environments, cloud-native architectures, and open-source code. The 2022 CISO Research Report indicates that while these technological advances enhance digital agility and customer experiences, they also complicate risk management and security. Nearly two-thirds of retail CISOs report difficulty in vulnerability management due to accelerated digital transformation, despite employing multilayered cybersecurity strategies. The reliance on open-source code introduces further risks, as evidenced by the widespread exposure to the Log4Shell vulnerability, which affected 97% of retail organizations. The report highlights the need for a cultural shift towards more agile practices, such as DevSecOps, and emphasizes the importance of integrating observability with security and enhancing strategies with AI and automation to effectively manage threats and protect ecommerce and supply chain operations.