Application vulnerabilities are a common challenge in modern software development, particularly within complex multicloud environments, but the OWASP Top 10 provides essential guidance for mitigating these security risks. The growing use of agile development, microservices, and serverless computing contributes to the increased potential for security vulnerabilities, with web app attacks being a rapidly expanding threat. DevSecOps automation offers a solution by integrating AIOps, risk prioritization, and runtime context throughout the software development lifecycle. Understanding and prioritizing prevalent vulnerabilities, such as those outlined in the OWASP Top 10, is crucial for effective prevention and mitigation. Additionally, leveraging platforms like Dynatrace Application Security, which uses AI and automation for vulnerability detection and management, helps DevSecOps teams distinguish and prioritize risks accurately. These tools enhance application security and build a robust DevSecOps culture by providing comprehensive coverage across traditional hosts, cloud workloads, and containers.