C# logging best practices are essential for optimizing application performance and debugging errors. To achieve this, developers can use native logging providers like TraceSource or specialized frameworks like log4net to enrich their logs with context and metadata. Streaming logs directly to the console or to a file can provide real-time visibility, but logging to a file is recommended for comprehensive monitoring. Enriching logs with metadata, standardizing their format, and logging exceptions with try/catch blocks can help extract valuable insights from log data. Centralized log management platforms like Datadog allow developers to collect, process, and analyze C# logs alongside other metrics and request traces, enabling better troubleshooting and investigation of issues.