You can create, delete, and configure video call rooms using the /rooms API endpoints, with limits on the number of available rooms depending on your paid API plan. Rooms have default expiration times or can be configured to auto-delete after a set time. You can also name your rooms with human-readable strings, manage access to meetings in private rooms, and delete existing rooms. The Daily.co API has various endpoints for listing rooms, creating meeting tokens, and controlling room privacy and configuration.