Amazon DynamoDB is a fully managed NoSQL database service that offers scalability and high performance, but can present challenges at scale, particularly for multi-tenant architectures. The use of a naive partition key, such as the tenant ID, can lead to the "noisy neighbor problem" where high traffic from one tenant can throttle the entire table. To overcome this, two strategies can be used: the Random Partition Key Strategy and the Sharded Partition Key Strategy. The first strategy uses a random partition key to increase throughput, while the second strategy splits a tenant's data into smaller partitions or shards to distribute it evenly across those shards, allowing for more efficient fetching of all items for a given tenant.