Couchbase's schema-less nature offers flexibility in designing NoSQL databases, allowing developers to bypass the time-consuming process of schema development, which is advantageous for quick prototyping and flexible document structures. A primary consideration when using Couchbase is deciding how to structure data—whether to keep related data in a single document for simplicity or separate it into multiple documents for more granular updates. Using the example of Breweries and their Beers, the text discusses pros and cons of various document structures, such as embedding all Beer data within a single Brewery document, which streamlines data retrieval but can lead to larger data requests, versus maintaining separate documents for each Beer and Brewery to maintain atomicity and ease of updates. Additionally, a third strategy involves using MapReduce to determine canonical data, allowing historical data to coexist without affecting current views. The choice of structure depends on the specific use case, balancing the need for quick data retrieval against the overhead of managing potentially large documents, and underscores the flexibility and power of Couchbase in accommodating diverse data modeling strategies.