Alexa Skills can be developed to operate on Amazon devices like the Echo by using serverless Azure Functions and a Couchbase backend hosted on Azure. This blog post details how to create such a skill, specifically designed to answer repetitive questions about Couchbase at developer events. The skill utilizes Azure Functions for HTTP requests and Couchbase for data storage, allowing for efficient querying and response tracking. By employing the AlexaSkills.NET library, developers can easily integrate and manage these skills. The outlined process includes setting up intents, designing documents for responses, and utilizing N1QL queries for data retrieval. The post also touches on the scalability of Couchbase and Azure Functions, suggesting that while the initial setup can handle small events, it can be expanded for larger deployments if necessary. The skill is in beta testing but demonstrates the potential of using serverless architecture for interactive applications.