The sixth session of Comet ML's Office Hours, part of the "Seven Simple Steps to Standardizing the Experiment" series, took place on February 9, 2022, featuring Dr. Doug Blank from Comet and Tiffany Fabianac of AstraZeneca. This session emphasized the importance of reproducibility in experiment management, highlighting that knowing exact hyperparameters and tracking changes is crucial. Doug Blank discussed the challenges of achieving true reproducibility, suggesting it should be integrated into company culture to guard against irreproducibility, while Tiffany Fabianac advocated for maintaining a focus on understanding models and their objectives as data evolves. A story from Doug's experience with developmental robotics illustrated the unpredictability of outcomes, underscoring the need for flexibility in machine learning lifecycles. The session also referenced the book "The Extended Mind" by Annie Murphy Paul and encouraged further exploration of topics through Comet's online platforms.