Cloudsmith can be easily integrated with Semaphore CI workflows to automate package management and deployment. By installing the Cloudsmith CLI and adding a secret containing the API key, users can push packages to a private Cloudsmith repository from their workflow. The integration involves creating a pipeline in Semaphore that includes two blocks: "Build Package" and "Push Package". The "Build Package" block builds and packages the source code, while the "Push Package" block pushes the package to the Cloudsmith repository using the API key. With this setup, users can automate their packaging process and take advantage of Continuous Packaging, a key component of modern DevOps workflows.