Text-to-speech (TTS) technology has significantly advanced, with Orpheus TTS, an open-source project by Canopy Labs, leading the way in producing human-like speech through cutting-edge language models and real-time streaming. Built on the Llama-3B language model, Orpheus TTS offers a dual availability model for organizations and researchers, providing finetuned models for production and pretrained base models for customization. The system supports multiple languages, voices, emotive tags, and zero-shot voice cloning, making it versatile for diverse applications such as customer service automation and creative content. The guide details deploying Orpheus TTS on Cerebrium, emphasizing scalable, low-latency inference and easy integration, which eliminates the need for managing complex infrastructure. As Orpheus TTS evolves, future versions promise enhanced functionality with expanded language support and improved model versioning, positioning it as a practical solution for enterprise and creative applications.