Microsoft Azure offers several cost optimization tips to help users save on their cloud computing bills, making it easier to manage expenses without sacrificing resources. By utilizing reserved instances with significant discounts, taking advantage of price matching with AWS costs, using built-in cost management tools such as advisor, calculator, budgets, and analysis, repackaging applications into containers, analyzing usage patterns and setting schedules for virtual machines, and deleting unused virtual disks, users can drastically reduce their cloud computing bill. These tips provide a comprehensive approach to optimizing Azure costs, allowing organizations to make the most of their IT budget while maintaining efficient resource utilization.