The spread of COVID-19 has caused a significant disruption globally, leading to widespread lockdowns, travel restrictions, and economic instability. The use of spatial data science and location-based data streams is crucial in understanding the dynamic nature of the virus's spread over time and space, enabling governments, institutions, and organizations to design, monitor, and optimize response measures. By analyzing online audience data, human mobility patterns, and other location-based indicators, insights can be gained on how social distancing efforts are being implemented across different regions and states, helping to identify areas where additional support is needed. Additionally, spatial data science can inform city emergency management services by providing critical information for better planning and resource allocation, such as identifying metro stations at risk of overcrowding and optimizing transportation services to ensure healthcare workers' safe passage. CARTO's technology and expertise are available to collaborate with organizations seeking to apply spatial analysis in the fight against COVID-19.