Lawrence Livermore National Laboratory (LLNL) is expanding its use of Claude for Enterprise to provide advanced AI capabilities to approximately 10,000 scientists, researchers, and staff, enhancing research in areas like nuclear deterrence, energy, and materials science. This expansion, one of the largest within the U.S. Department of Energy's national laboratory system, aims to transform government research operations by enabling scientists to process complex datasets, generate hypotheses, and explore new research directions with AI that understands scientific context. The partnership between LLNL and Anthropic exemplifies how AI can enhance scientific research and national security, providing a model for other national labs. Claude's application suite offers robust security features and large context processing capabilities, allowing comprehensive analysis of experiments and simulations. LLNL's scientists are leveraging Claude across various disciplines, accelerating scientific discovery, enhancing collaboration, and streamlining operations to focus on high-impact research. This initiative follows a successful pilot program and showcases Claude's potential in advancing scientific national security research. Organizations interested in adopting Claude for Enterprise can contact the public sector team for more information.