To get started with AWS and Kubernetes infrastructure, three essential requirements must be met: an AWS account, an administrator user account with programmatic access, and the installation of the official AWS command line tool. To obtain an AWS account, visit Amazon's website, create a new account, or check if your organization already has one. For the user account, sign in to the User Management Screen, add a new user with programmatic access and AWS Management Console access, select "AdministratorAccess" for full access, and copy the API Access Key ID and Secret Access Key. Once installed, configure the AWS CLI by running `aws configure` and providing the necessary credentials, including the Access Key ID, Secret Access Key, default region name, and output format.